Identification and functional analysis of choline transporter in tongue cancer: A novel molecular target for tongue cancer therapy
نویسندگان
چکیده
منابع مشابه
Outcome of tongue cancer and early diagnosis
Back ground and Objective:Oral cancer is primarily a disease of epithelial origin. The tongue is the most common site of oral cancer. The aim of this study was to determine the frequency of tongue cancer and signs, symptoms, clinical features, and site of lesions in addition to factors affected this cancer. Materials Methods and:Twenty eight medical records of patients who a...
متن کاملepidemiologic and clinicopathologic characteristics of tongue cancer in iranian patients
oral cancer is considered a great threat to public health. tongue cancer accounts for nearly 30% of all oral cancers and usually seen in 50 to 60 year old men. oropharyngeal cancers account for 3% of all cancers in iran; as reported in 2003. the present study was designed to assess the epidemiologic and clinicopathologic characteristics of tongue cancer patients in two tehran's referral univers...
متن کاملOral Tongue Cancer
The anterior two thirds of the tongue lie in the oral cavity (mobile tongue). The posterior third (base of tongue) is in the oropharynx and the junction between the two is at the insertion of the anterior faucial pillar and the line of the circumvallate papillae. Eighty-five per cent of tumours arise on the lateral border of the oral tongue, 10 to 15% on the ventral surface and 5% or less from ...
متن کاملoutcome of tongue cancer and early diagnosis
back ground and objective:oral cancer is primarily a disease of epithelial origin. the tongue is the most common site of oral cancer. the aim of this study was to determine the frequency of tongue cancer and signs, symptoms, clinical features, and site of lesions in addition to factors affected this cancer. materials methods and:twenty eight medical records of patients who admitted for tongue...
متن کاملThe polycomb group protein EZH2 is a novel therapeutic target in tongue cancer
EZH2, a core member of the Polycomb Repressor Complex 2 (PRC2), mediates transcriptional silencing by catalyzing the trimethylation of histone 3 lysine 27 (H3K27), which plays key roles in cancer initiation and progression. Here, we investigated the expression pattern and biological roles of EZH2 in tongue tumorigenesis by loss-of-function assays using small interference RNA and EZH2 inhibitor ...
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ژورنال
عنوان ژورنال: Journal of Pharmacological Sciences
سال: 2016
ISSN: 1347-8613
DOI: 10.1016/j.jphs.2016.04.022